This imbalance was addressed by including practice type, which is the likely driver of imbalance in race and insurance, in the response models. Remaining imbalance in season was both restricted to a single season and inconsistent and, thus, likely to be an artifact.
Although this could have resulted in uncontrolled confounding, results were robust to multiple analyses. Among children with acute respiratory tract infections, broad-spectrum antibiotics were not associated with better clinical or patient-centered outcomes compared with narrow-spectrum antibiotics, and were associated with higher rates of adverse events.
Corresponding Author: Jeffrey S. Author Contributions: Dr Gerber had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Dr Zaoutis reported serving as a consultant to T2 Biosystems and Nabriva. Dr Fiks reported receiving a Pfizer independent research grant. No other disclosures were reported.
Disclaimer: The statements presented in this publication are solely the responsibility of the authors and do not necessarily represent the views of PCORI or its board of governors or methodology committee.
Mr Massey received administrative support for this project, which included compensation from PCORI for help with recruiting practices for the intervention. We also thank the family advisory council not compensated for their support and guidance on this project from conception through execution; Susan L.
Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy Continue. Figure 1. View Large Download. Figure 2. Table 1. Table 2. Table 3. Table 4. Patient-Centered Outcomes in the Prospective Cohort. Diagnosis codes for acute respiratory tract infections eTable 2. Appropriate antibiotics with classification for treatment of acute respiratory tract infections eTable 3. Odds ratios for clinical outcomes eTable 5.
Clinical outcomes, results stratified by diagnosis eTable 6. Prospective patient-centered outcome cohort: Comparison of patient characteristics of children who did and did not complete the day interview eTable 8. Odds ratios for patient-centered outcomes eTable Patient-centered outcomes, results stratified by diagnosis eText eFigure. Trends of outpatient prescription drug utilization in US children, PubMed Google Scholar Crossref.
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