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They Hear You. Solr Mobile Search. Share Buttons. Page title Naltrexone. What Is Naltrexone? How Naltrexone Works Naltrexone is not an opioid, is not addictive, and does not cause withdrawal symptoms with stop of use. Naltrexone for Opioid Use Disorder To reduce the risk of withdrawal symptoms, patients should wait at least 7 days after their last use of short-acting opioids and 10 to 14 days for long-acting opioids, before starting naltrexone.
Learn more about OUD. Naltrexone for Alcohol Use Disorder When starting naltrexone for AUD, patients must not be physically dependent on alcohol or other substances. Learn more about AUD. Accidental overdose can happen in two ways. Naltrexone blocks the effects of opioids, such as heroin or opioid pain medicines. Patients who try to overcome this blocking effect by taking large amounts of opioids may experience serious injury, coma, or death.
After receiving a dose of naltrexone, the blocking effect slowly decreases and completely goes away over time. Patients who are taking naltrexone for an OUD can become more sensitive to the effects of opioids at the dose used before, or even lower amounts. Using opioids while on naltrexone can lead to overdose and death. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:. A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into the buttocks gluteal muscle. It is usually given every 4 weeks or once a month. Naltrexone injection should only be given to alcohol-dependent patients who can abstain from drinking alcohol and does not need an overnight stay in the hospital.
This medicine usually comes with a Medication Guide. Read the information carefully and make sure you understand it before receiving this medicine.
If you have any questions, ask your doctor. If you miss your scheduled dose, call your doctor to make another appointment as soon as possible. It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
Blood and urine tests may be needed to check for unwanted effects. This medicine may cause injection site reactions.
Check with your doctor right away if you have bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site.
Check with your doctor right away if you have dark urine, general tiredness and weakness, light-colored stools, nausea and vomiting, upper right stomach pain, and yellow eyes and skin. These may be symptoms of serious liver problems.
Check with your doctor right away if you have chest pain, dry cough, fever, general feeling of tiredness or weakness, rapid breathing, skin rash, or trouble breathing. These may be symptoms of a lung problem called eosinophilic pneumonia. This medicine may cause a serious type of allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention.
Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
You will need to stop using opioids narcotics for at least 7 to 10 days before you can start receiving naltrexone injection. Your doctor may need to do the naloxone challenge test or a urine test for opioids to make sure you are opioid-free. This medicine may increase thoughts of suicide. Tell your doctor right away if you start to feel more depressed.
Also tell your doctor right away if you have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly.
Make sure your caregiver knows if you feel tired all the time, sleep a lot more or a lot less than usual, feel hopeless or helpless, or if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared.
Remember that use of naltrexone is only part of your treatment. Do not try to overcome the effects of naltrexone injection by taking narcotics. You may be more sensitive to the effects of narcotics than you were before beginning naltrexone treatment.
You could overdose and develop serious problems, including coma or death. Symptoms of an opioid overdose include: drowsiness, extreme dizziness or weakness, irregular, fast or slow, or shallow breathing, pale or blue lips, fingernails, or skin, pinpoint pupils, relaxed and calm, slow heartbeat or breathing, seizures, sleepiness, trouble breathing, or cold, clammy skin.
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The Dosage and Administration, Section 2. To provide the most accurate information and directions, your search will open in Google Maps. You are about to enter a site for U. Click "Continue" below to confirm that you're a licensed U. Vivitrol2gether can contact injection sites to confirm treatment availability. Find A Treatment Provider. If you are a healthcare professional and would like to participate in the Provider Locator, please download the Provider Locator Agreement form.
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I agree to the terms and conditions. Service: Prescribers. Injection Providers. Facility Type: Inpatient. Retail Pharmacy Injection Provider. Retail Clinic Injection Provider. Facility Treats: Alcohol Dependence. Opioid Dependence. Loading new results. No results found. Clear filters. You can accidentally overdose in two ways. Do not try to overcome this blocking effect by taking large amounts of opioids—this can lead to serious injury, coma, or death.
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